Crude extract from viscum album coloratum, and proteins and lectins isolated therefrom
Disclosed is an extract from Korean mistletoe KM-110, which is of immunity enhancement and activity against tumor metastasis and can be used as an adjuvant material for vaccines applicable for the induction of humoral and cell-mediated immunity. Also disclosed are its fractions, a protein fraction K...
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Main Authors | , , , , , , , , , |
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Format | Patent |
Language | English French German |
Published |
07.02.2001
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | Disclosed is an extract from Korean mistletoe KM-110, which is of immunity enhancement and activity against tumor metastasis and can be used as an adjuvant material for vaccines applicable for the induction of humoral and cell-mediated immunity. Also disclosed are its fractions, a protein fraction KM-AS, a lectin fraction KML-C, lectin components KML-IIU and KML-IIL, which both are further purified from lectin fraction KML-C, a protein KMHBP which is obtained through heparin binding chromatogtaphy eluting with NaCl from a fraction C-free AS which is a portion of the KM-AS free of KML-C, and a mixture KM of the KMHBP and the KML-C. They are revealed to their roles in the humoral and cell-mediated immunity enhancement and antitumoral activity. |
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Bibliography: | Application Number: EP20000402168 |