Heterocyclic compounds as retinoic acid receptor antagonists

Compounds represented by the general formula (2-I) or physiologically acceptable salts thereof: The compounds according to the present invention exhibit extremely high ability to bind RARs and are effective for treating various kind of diseases such as abnormality in cornification and rheumatoid art...

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Main Authors KIKUCHI, KOUICHI, HIDA, TAKAYUKI, AOSHIMA, SEIKO, YAMANAKA, TAKASHI, OGASAWARA, AICHI, NAGAI, MITSUO, HISHINUMA, IEHARU, MIYAMOTO, NORIMASA, ASADA, MAKOTO, YOSHIMURA, HIROYUKI, HIBI, SHIGEKI, TAI, KENJI, NAGAKAWA, JUNICHI, ABE, SHINYA, TAGAMI, KATSUYA
Format Patent
LanguageEnglish
French
German
Published 01.10.2003
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CALCULATING
CHEMISTRY
COMPUTING
COUNTING
ELECTRIC DIGITAL DATA PROCESSING
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PHYSICS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds represented by the general formula (2-I) or physiologically acceptable salts thereof: The compounds according to the present invention exhibit extremely high ability to bind RARs and are effective for treating various kind of diseases such as abnormality in cornification and rheumatoid arthritis.
Bibliography:Application Number: EP20000119709