QUINOLINE CARBOXAMIDES AS TNF INHIBITORS AND AS PDE-IV INHIBITORS

The subject invention concerns novel compounds of the general formula (i) that are useful in treating disease states, such as those states associated with proteins that mediate cellular activity. The compounds of the subject invention can be used, for example, to inhibit tumor necrosis factor and/or...

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Bibliographic Details
Main Authors LOWE, CHRISTOPHER, MONTANA, JOHN GARY, DYKE, HAZEL JOAN, SABIN, VERITY MARGARET, KENDALL, HANNAH JAYNE
Format Patent
LanguageEnglish
French
German
Published 27.08.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The subject invention concerns novel compounds of the general formula (i) that are useful in treating disease states, such as those states associated with proteins that mediate cellular activity. The compounds of the subject invention can be used, for example, to inhibit tumor necrosis factor and/or phosphodiesterase IV, The subject invention also concerns methods for treating disease states using the compounds of the invention.
Bibliography:Application Number: EP19970923191