2-Aza-bicyclo¬2.2.1 heptane derivatives and their use as rotamase inhibitors

This invention relates to novel azabicyclic compounds of the formula wherein R , Q and Z are defined as in the specification, pharmaceutical compositions containing them, and the use of such compounds for the treatment of neurodegenerative diseases and other disorders involving nerve damage.

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Bibliographic Details
Main Authors BLAKE, JAMES FRANCIS, NAGEL, ARTHUR ADAM
Format Patent
LanguageEnglish
French
German
Published 06.10.1999
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to novel azabicyclic compounds of the formula wherein R , Q and Z are defined as in the specification, pharmaceutical compositions containing them, and the use of such compounds for the treatment of neurodegenerative diseases and other disorders involving nerve damage.
Bibliography:Application Number: EP19990301782