BACTERIAL DONOR CELL USEFUL IN CONJUGATION
The present invention relates to a modified bacterial donor cell useful in conjugation, the cell containing i) a plasmid comprising a DNA construct encoding the polypeptide of interest, and at least one cis-acting DNA sequence required for the transfer of said plasmid by conjugation in the presence...
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Main Authors | , |
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Format | Patent |
Language | English French German |
Published |
17.07.2002
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a modified bacterial donor cell useful in conjugation, the cell containing i) a plasmid comprising a DNA construct encoding the polypeptide of interest, and at least one cis-acting DNA sequence required for the transfer of said plasmid by conjugation in the presence of a trans-acting mobilizing element, and ii) at least one DNA sequence encoding said trans-acting mobilizing element, wherein the donor cell has a reduced capacity, relative to a parent cell, of producing a bactericidal agent which kills or prevents growth in a population of recipient cells. |
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Bibliography: | Application Number: EP19970903024 |