Calcium phosphate cement and calcium phosphate cement composition

• Main Authors: SAWAMURA, TAKENORI, OKUYAMA, MASAHIKO, HATTORI, MASATERU
• Format: Patent
• Language: English; French; German
• Published: 03.03.1999
• Edition: 6
• Subjects: ARTIFICIAL STONE; BANDAGES, DRESSINGS OR ABSORBENT PADS; CEMENTS; CERAMICS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDINGMATERIALS; CONCRETE; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; LIME, MAGNESIA; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROSTHESES; REFRACTORIES; SLAG; TREATMENT OF NATURAL STONE; TREATMENT OR PROTECTION OF EYES OR EARS

A calcium phosphate cement and a calcium phosphate cement composition are disclosed. The calcium phosphate cement comprises a calcium phosphate powder having an average particle diameter of 20 mu m or smaller and a tap density of 35% or higher, and a polysaccharide. The polysaccharide is preferably a dextran sulfate (e.g., dextran sulfate sodium) having an average particle diameter of 0.1 to 100 mu m. The calcium phosphate cement composition comprises the above specific calcium phosphate powder and a liquid for cement mixing comprising an aqueous solution containing 30 to 60 wt% dextran sulfate (e.g., dextran sulfate sodium or dextran sulfate potassium). The calcium phosphate powder preferably comprises a tetracalcium phosphate powder and an equimolar amount of a calcium hydrogen phosphate powder as main components.