CHO (Chinese Hamster Ovary) glycosylated antibodies and their use in therapy
The invention relates to a CHO cell-line capable of producing antibody, the cell-line having been co-transfected with a vector capable of expressing the light chain of the antibody and a vector capable of expressing the heavy chain of the antibody wherein the vectors contain independently selectable...
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Main Author | |
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Format | Patent |
Language | English French German |
Published |
04.02.1998
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to a CHO cell-line capable of producing antibody, the cell-line having been co-transfected with a vector capable of expressing the light chain of the antibody and a vector capable of expressing the heavy chain of the antibody wherein the vectors contain independently selectable markers; also included is a CHO cell-line capable of producing a human antibody or an altered antibody, the cell-line having been transfected with a vector capable of expressing the light chain of the antibody and the heavy chain of the antibody; process for the production of antibody using a CHO cell-line and antibody having CHO glycosylation. |
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Bibliography: | Application Number: EP19970201842 |