TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS

Tricyclic compound of the general Formula I: I as defined herein which exhibit antagonist activity at V1 and/or V2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and process for...

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Main Authors ALBRIGHT, JAY, DONALD, VENKATESAN, ARANAPAKAM, MUDUMBAI, DU, XUEMEI, DELOS SANTOS, EFREN, GUILLERMO, REICH, MARVIN, FRED
Format Patent
LanguageEnglish
French
German
Published 19.12.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Tricyclic compound of the general Formula I: I as defined herein which exhibit antagonist activity at V1 and/or V2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and process for preparing such compounds.
Bibliography:Application Number: EP19960903777