Preparation and use of salts of 6,8-bis(amidiniumthio)octanoic acid

6,8-Bis(amidiniumthio)octanoic acid salts for formula CH2(SC(NH2)2<+>X<->)-CH2-CH(SC(NH2)2<+>Y<->)-CH 2-CH2-CH2-CH2-COOR (III) are new. R = H or 1-3C alkyl; X<->, Y<-> = anions of a mineral acid, alkyl- or arylsulphonic acid, or carboxylic acid. Also claimed is th...

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Main Authors BEISSWENGER, THOMAS, GEWALD, RAINER, RAUTENBERG, STEPHAN, OLBRICH, ALFRED DR, KLENK, HERBERT, BETHGE, HORST, HUTHMACHER, KLAUS, HUEBNER, FRANK, MOELLER, ROLAND, SATOR, GERHARD
Format Patent
LanguageEnglish
French
German
Published 19.11.1997
Edition6
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:6,8-Bis(amidiniumthio)octanoic acid salts for formula CH2(SC(NH2)2<+>X<->)-CH2-CH(SC(NH2)2<+>Y<->)-CH 2-CH2-CH2-CH2-COOR (III) are new. R = H or 1-3C alkyl; X<->, Y<-> = anions of a mineral acid, alkyl- or arylsulphonic acid, or carboxylic acid. Also claimed is the use of (III) for the synthesis of racemic 6,8-dimercaptooctanoic acid, (+)-6,8-dihydrolipoic acid, (-)-6,8-dihydrolipoic acid, racemic alpha -lipoic acid, (+)- alpha -lipoic acid or (-)- alpha -lipoic acid.
Bibliography:Application Number: EP19970100224