NOVEL 1,1-BIS(HETEROAZOLYL)ALKANE DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE AGENTS

PCT No. PCT/SE95/00604 Sec. 371 Date Jan. 29, 1996 Sec. 102(e) Date Jan. 29, 1996 PCT Filed May 29, 1995 PCT Pub. No. WO95/33747 PCT Pub. Date Dec. 14, 1995The present invention relates to novel heterocyclic compounds having the general formula (1) ly O, S or Se; Y1 and Y2 are independently C or N w...

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Bibliographic Details
Main Authors GRAY, DUNCAN, ALASTAIR, BOAR, BERNARD, ROBIN, O'SHEA, DENNIS, MARK
Format Patent
LanguageEnglish
French
German
Published 02.04.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PCT No. PCT/SE95/00604 Sec. 371 Date Jan. 29, 1996 Sec. 102(e) Date Jan. 29, 1996 PCT Filed May 29, 1995 PCT Pub. No. WO95/33747 PCT Pub. Date Dec. 14, 1995The present invention relates to novel heterocyclic compounds having the general formula (1) ly O, S or Se; Y1 and Y2 are independently C or N with the proviso that at least one of Y1 and Y2 is N; Y3 and Y4 are independently C or N with the proviso that at least one of Y3 and Y4 is N; R1 and R2 each represent one or more groups independently selected from H, lower alkyl, lower alkoxy-lower alkyl, hydroxy-lower alkyl, lower acyloxy-lower alkyl or CF3; and A is geometrical and optical isomers and racemates thereof where such isomers exist, as well as pharmaceutically acceptable acid addition salts thereof and solvates thereof; having therapeutic activity, processes and intermediates for their preparation, pharmaceutical formulations containing said compounds and the medicinal use of said compounds.
Bibliography:Application Number: EP19950922031