NOVEL FUNCTIONALIZED HYDROPHILIC ACRIDINIUM ESTERS

Novel acridinium esters that are useful, either alone or when incorporated into liposomes, as chemiluminescent agents in binding assays (e.g., immunoassays and gene probe assays) with improved sensitivity are disclosed. In addition, the synthesis of these esters and their use in assays for detecting...

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Bibliographic Details
Main Authors MCCUDDEN, CONSTANCE, R, TIRRELL, STEPHEN, M, SOTIRIOU-LEVENTIS, CHARIKLIA, JIANG, QINGPING, KILROY, JOHN, P, LAW, SAY-JONG, NATRAJAN, ANAND, CONNOLLY, PETER, B
Format Patent
LanguageEnglish
French
German
Published 22.01.1997
Edition6
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
STEROIDS
TESTING
VINEGAR
WINE
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Summary:Novel acridinium esters that are useful, either alone or when incorporated into liposomes, as chemiluminescent agents in binding assays (e.g., immunoassays and gene probe assays) with improved sensitivity are disclosed. In addition, the synthesis of these esters and their use in assays for detecting an analyte is described. In particular, assays for testosterone and the Rubella virus are disclosed.
Bibliography:Application Number: EP19950913298