PROCESS FOR PREPARING FINE PARTICLE PHARMACEUTICAL FORMULATIONS

A process for preparing fine particle pharmaceutical formulations having improved throughput and producing greater uniformity of particle size. The process relates to adding to the dry components of the formulation prior to the steps of wetting, extrusion and spheronization, an extrusion aid materia...

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Main Authors BRISKIN, JACQUELINE, E, GUPTA, PRAMOD, K, KOHLER, ROBERT, W, SEMLA, SUSAN, J, LOYD, CLAUD
Format Patent
LanguageEnglish
French
German
Published 04.12.1996
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A process for preparing fine particle pharmaceutical formulations having improved throughput and producing greater uniformity of particle size. The process relates to adding to the dry components of the formulation prior to the steps of wetting, extrusion and spheronization, an extrusion aid material selected from pharmaceutically acceptable oils and waxes having a drop point between about 15 DEG C. and 115 DEG C.
Bibliography:Application Number: EP19950909559