Agents for prevention or treatment of chronic rheumatism and sepsis

The pharmaceutical use of 1-cinnamoyl-2-pyrrolidinone derivatives having the activities to inhibit the production of IL-1 beta and the release of TNF alpha . Those derivatives are useful in the treatment or prophylaxis of the diseases such as chronic rheumatism and sepsis.

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Bibliographic Details
Main Authors SAITO, YUKIO, HATANAKA, SHIGEO, ARIGA, MASATO, MOMOSE, KENICHI, KATSUYAMA, KOICHI
Format Patent
LanguageEnglish
French
German
Published 01.04.1998
Edition6
Subjects
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Summary:The pharmaceutical use of 1-cinnamoyl-2-pyrrolidinone derivatives having the activities to inhibit the production of IL-1 beta and the release of TNF alpha . Those derivatives are useful in the treatment or prophylaxis of the diseases such as chronic rheumatism and sepsis.
Bibliography:Application Number: EP19950120407