Cyclosporin containing multiple emulsions

The invention relates to an oral multiple emulsion pre concentrate comprising a surface active agent, ethanol a lipophilic and/or an amphiphilic solvent. The composition comprising from about 5 to about 30 % by weight of cyclosporin, from about 5 to about 30 % by weigh of tocopheryl polyethylene gly...

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Main Authors KOVACS, ISTVAN, JANCSO, SANDOR, ERDOEHATI, ERZSEBET, JARABIN, MARTA, BALAZS, ZOLTAN, VARGA, ZSOLT, KISS, ILDIKO, TAKACS, ERZSEBET, KORCSMAROS NEE KANYA, ILDIKO, JUSZTIN, MARTA, HEIM, CSABA
Format Patent
LanguageEnglish
French
German
Published 04.12.1996
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to an oral multiple emulsion pre concentrate comprising a surface active agent, ethanol a lipophilic and/or an amphiphilic solvent. The composition comprising from about 5 to about 30 % by weight of cyclosporin, from about 5 to about 30 % by weigh of tocopheryl polyethylene glycol carboxylic acid ester, from about 5 to about 20 % by weight of ethanol, from about 20 to about 55 % by weight of a lipophylic solvent and/or from about 10 to about 55 % by weight of an amphiphilic solvent, and if desired from about 10 to about 20 % by weight of co-tenside.
Bibliography:Application Number: EP19950106655