Use of 5-Thia-1,4-diazabicyclo [4.2.0] octane-3,8-dioxo compounds in antitumor therapy

• Main Authors: HORVATIC, MARJETA, M. SC, TOMIC, MIRJANA M. SC, MANDIC, ZORA M. SC, GRDISA, MIRA, D. SC, LUKIC, IRENA, M. SC, KOVACEVIC, MICE, D. SC, PAVELIC, KRESIMIR, D. SC, HERAK, JURE J., D. SC
• Format: Patent
• Language: English; French; German
• Published: 18.03.1998
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to the use of 5-thia-1,4-diazabicycloÄ4.2.0Üoctane-3,8-dioxo compounds of the general formula I, wherein the radicals have the following meanings: R is hydrogen, halogen, R is hydrogen, halogen, amino, PhCH2CONH, PhOCH2CONH, phthalimido, o-MeNHCOC6H4CONH, 3-o-chlorophen...