Heterocyclic derivatives of N-phenylamides

New central nervous system agents conform to formula I: wherein R = H or C1-4 alkoxy; X = CH or N; Y = NH, O or S; Z = C1-4 alkyl, C3-6 cycloalkyl, C2-3 alkenyl, NH2, C1-4 alkylamino, or C1-4 alkoxyalkyl, with the proviso that Z may not be CH3 when R=H, X=CH, and Y=NH and Z may not be CH3 when R=H,...

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Bibliographic Details
Main Authors ORTIZ, ASTRID A, WATSON, BRETT T
Format Patent
LanguageEnglish
French
German
Published 13.03.1996
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:New central nervous system agents conform to formula I: wherein R = H or C1-4 alkoxy; X = CH or N; Y = NH, O or S; Z = C1-4 alkyl, C3-6 cycloalkyl, C2-3 alkenyl, NH2, C1-4 alkylamino, or C1-4 alkoxyalkyl, with the proviso that Z may not be CH3 when R=H, X=CH, and Y=NH and Z may not be CH3 when R=H, X=N and Y=NH and NHC(O)Z is in the para- position.
Bibliography:Application Number: EP19950113475