METHOD OF ALKYLATING OESTRONE DERIVATIVES

PCT No. PCT/EP93/02905 Sec. 371 Date May 26, 1995 Sec. 102(e) Date May 26, 1995 PCT Filed Oct. 21, 1993 PCT Pub. No. WO94/09024 PCT Pub. Date Apr. 28, 1994The invention relates to a process for the alkylation of estrone derivatives, which is characterized in that a suspension of the estrone derivati...

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Bibliographic Details
Main Authors HUEBL, DIETER, SEILZ, CARSTEN
Format Patent
LanguageEnglish
French
German
Published 09.08.1995
Edition6
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Summary:PCT No. PCT/EP93/02905 Sec. 371 Date May 26, 1995 Sec. 102(e) Date May 26, 1995 PCT Filed Oct. 21, 1993 PCT Pub. No. WO94/09024 PCT Pub. Date Apr. 28, 1994The invention relates to a process for the alkylation of estrone derivatives, which is characterized in that a suspension of the estrone derivatives in dimethylformamide is produced and carbonic acid diester and guanidine and/or alkyl guanidines are dissolved in it and in the largely oxygen-free mixture, the reaction is performed at 100 DEG -200 DEG C. under the reaction pressure being established.
Bibliography:Application Number: EP19930923513