AMIDE DERIVATIVES
PCT No. PCT/GB93/02090 Sec. 371 Date Apr. 11, 1995 Sec. 102(e) Date Apr. 11, 1995 PCT Filed Oct. 8, 1993 PCT Pub. No. WO94/08983 PCT Pub. Date Apr. 28, 1994A novel asymmetric synthesis is provided for preparing optically active amides of formula (A) and their salts. (A) In the formula, X represent -...
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Main Author | |
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Format | Patent |
Language | English French German |
Published |
14.07.1999
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | PCT No. PCT/GB93/02090 Sec. 371 Date Apr. 11, 1995 Sec. 102(e) Date Apr. 11, 1995 PCT Filed Oct. 8, 1993 PCT Pub. No. WO94/08983 PCT Pub. Date Apr. 28, 1994A novel asymmetric synthesis is provided for preparing optically active amides of formula (A) and their salts. (A) In the formula, X represent -N- or -CH-, R represents a mono or bicyclic aryl or heteroaryl group, R1 is an aryl or heteroaryl radical, and R2 and R3 have specified meanings. The products are useful as 5-HT1A antagonists. Novel diesters of formula D useful as intermediates in the process are also disclosed. (D) |
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Bibliography: | Application Number: EP19930922576 |