PYRIMIDINE COMPOUND

A pyrimidine derivative represented by general formula (II) or (III) and a salt thereof, both having selective acetylcholine esterase inhibitor and type A monoamine oxidase inhibitor effects, thus being useful as antidepressant and senile dementia remedy. In said formulae, R and R represent each H,...

Full description

Saved in:
Bibliographic Details
Main Authors FUJIWARA, HIROSHI, ANPEIJI, SHIGEHARU, KIMURA, TOMIO, KUROKI, YOSHIAKI
Format Patent
LanguageEnglish
French
German
Published 19.07.2000
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:A pyrimidine derivative represented by general formula (II) or (III) and a salt thereof, both having selective acetylcholine esterase inhibitor and type A monoamine oxidase inhibitor effects, thus being useful as antidepressant and senile dementia remedy. In said formulae, R and R represent each H, halogen, amino, nitro, (un)substituted alkyl, alkoxy or alkoxycarbonyl, provided that R and R may be combined together to represent (un)substituted alkylene; R represents aralkyl or heteroaryl-alkyl; R represents H or acyl; R represents H, OH or alkoxy; R represents H, halogen, alkyl or alkoxy; X represents -CH=, -CH=CH-(CH2)p-, -CH2- or -CH2CH2-(CH2)p-; Y represents =CH-(CH2)p-, -CH2-(CH2)p-, single bond or double bond; p represents 0 or 1; and symbol @ represents either single or double bond.
Bibliography:Application Number: EP19930921102