PREVENTING TISSUE ADHESION USING -i(IN SITU) MODIFICATION OF ALGINATE
A method of modifying salts of alginic acid in situ for prevention and treatment of various intra-articular and extra-articular (spine) complications modifies the alginate in situ to an insoluble gel. This in situ modification provides a final product which can be compressed within the intra-articul...
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Main Authors | , , |
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Format | Patent |
Language | English French German |
Published |
20.11.1996
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Abstract | A method of modifying salts of alginic acid in situ for prevention and treatment of various intra-articular and extra-articular (spine) complications modifies the alginate in situ to an insoluble gel. This in situ modification provides a final product which can be compressed within the intra-articular space thus remaining localized. The modified material can have varied mechanical strengths and thus varied degradation times and can serve as a matrix for localizing and slowly releasing therapeutic agents. The modified material is biocompatible and biodegradable, thus requiring no reoperation for removal. |
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AbstractList | A method of modifying salts of alginic acid in situ for prevention and treatment of various intra-articular and extra-articular (spine) complications modifies the alginate in situ to an insoluble gel. This in situ modification provides a final product which can be compressed within the intra-articular space thus remaining localized. The modified material can have varied mechanical strengths and thus varied degradation times and can serve as a matrix for localizing and slowly releasing therapeutic agents. The modified material is biocompatible and biodegradable, thus requiring no reoperation for removal. |
Author | BARRY, JAMES J HIGHAM, PAUL A ABERMAN, HAROLD M |
Author_xml | – fullname: BARRY, JAMES J – fullname: ABERMAN, HAROLD M – fullname: HIGHAM, PAUL A |
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DocumentTitleAlternate | VERWENDUNG VON IN SITU MODIFIKATION VON ALGINAT ZUR VORBEUGUNG VON GEWEBEADHÄSION PREVENTION DE L'ADHESION TISSULAIRE PAR MODIFICATION -i(IN SITU) D'ALGINATE |
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PublicationYear | 1996 |
RelatedCompanies | HOWMEDICA INC |
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Snippet | A method of modifying salts of alginic acid in situ for prevention and treatment of various intra-articular and extra-articular (spine) complications modifies... |
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SubjectTerms | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | PREVENTING TISSUE ADHESION USING -i(IN SITU) MODIFICATION OF ALGINATE |
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