PREVENTING TISSUE ADHESION USING -i(IN SITU) MODIFICATION OF ALGINATE
A method of modifying salts of alginic acid in situ for prevention and treatment of various intra-articular and extra-articular (spine) complications modifies the alginate in situ to an insoluble gel. This in situ modification provides a final product which can be compressed within the intra-articul...
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Main Authors | , , |
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Format | Patent |
Language | English French German |
Published |
20.11.1996
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | A method of modifying salts of alginic acid in situ for prevention and treatment of various intra-articular and extra-articular (spine) complications modifies the alginate in situ to an insoluble gel. This in situ modification provides a final product which can be compressed within the intra-articular space thus remaining localized. The modified material can have varied mechanical strengths and thus varied degradation times and can serve as a matrix for localizing and slowly releasing therapeutic agents. The modified material is biocompatible and biodegradable, thus requiring no reoperation for removal. |
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Bibliography: | Application Number: EP19930908588 |