Process for preparing 2-amino-3-hydroxy acids

The invention provides a process for preparing 2-amino-3-hydroxy acids. The process comprises mixing an aldehyde, and glycine with Escherichia coli serine hydroxymethyltransferase in the presence of pyridoxal 5'-phosphate to form the corresponding L-erythro-2-amino-3-hydroxy acid.

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Bibliographic Details
Main Authors DOTZLAF, JOE EDWARD, VICENZI, JEFFREY THOMAS, KREUZMAN, ADAM JOSEPH, KROEFF, EUGENE PAUL, QUEENER, STEPHEN WYATT, ZOCK, JOSEPH MARTIN, YEH, WU-KUANG, GAZAK, ROBERT JAMES
Format Patent
LanguageEnglish
French
German
Published 14.12.1994
Edition5
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention provides a process for preparing 2-amino-3-hydroxy acids. The process comprises mixing an aldehyde, and glycine with Escherichia coli serine hydroxymethyltransferase in the presence of pyridoxal 5'-phosphate to form the corresponding L-erythro-2-amino-3-hydroxy acid.
Bibliography:Application Number: EP19940303654