PRODUCTION AND USE OF MULTIMERIC HEMOGLOBINS
Multimeric hemoglobin-like proteins are obtained by crosslinking cysteines, natural or artificial, of the component tetramers, or by genetically fusing globin-like domains of one tetramer with those of another, by means of an interdomain spacer sequence. Artificial cysteines are introduced selective...
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Main Authors | , , |
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Format | Patent |
Language | English French German |
Published |
17.06.1998
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | Multimeric hemoglobin-like proteins are obtained by crosslinking cysteines, natural or artificial, of the component tetramers, or by genetically fusing globin-like domains of one tetramer with those of another, by means of an interdomain spacer sequence. Artificial cysteines are introduced selectively in a single globin-like domain per tetramer to control polymerization. |
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Bibliography: | Application Number: EP19920925173 |