NITROGENOUS HETEROCYCLIC COMPOUND

• Main Authors: AKITA, YASUNORI, KIMURA, TEIJI, IKUTA, HIRONORI, SAEKI, TAKAO, SOUDA, SHIGERU, WATANABE, NOBUHISA, MATSUI, MAKOTO, MOCHIDA, HISATOSHI, TAKASE, YASUTAKA, TOKUMURA, TADAKAZU, ADACHI, HIDEYUKI
• Format: Patent
• Language: English; French; German
• Published: 09.01.2002
• Edition: 7
• Subjects: BEARINGS; BLASTING; CHEMISTRY; ELEMENTS OR CRANKSHAFT MECHANISMS; ENGINEERING ELEMENTS AND UNITS; FLEXIBLE SHAFTS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVEFUNCTIONING OF MACHINES OR INSTALLATIONS; HEATING; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; LIGHTING; MECHANICAL ENGINEERING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; ROTARY BODIES OTHER THAN GEARING ELEMENTS; SERVICING, CLEANING, REPAIRING, SUPPORTING, LIFTING, ORMANOEUVRING OF VEHICLES, NOT OTHERWISE PROVIDED FOR; SHAFTS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THERMAL INSULATION IN GENERAL; TRANSPORTING; VEHICLES IN GENERAL; WEAPONS

A nitrogenous heterocyclic compound represented by general formula (I) or a pharmacologically acceptable salt thereof, efficacious in treating various ischemic cardiac diseases, wherein ring A represents a benzene, pyridine or cyclohexane ring; ring B represents a pyridine, pyrimidine or imidazole ring; R , R , R and R represent each hydrogen, halogen, lower alkoxy, etc.; R represents -NR R (wherein R and R represent each hydrogen, lower alkyl, etc.), etc.; and R represents (a) (wherein R represents hydrogen, lower alkyl, etc.; R , R and R represent each hydrogen, halogen, hydroxy, etc.; and r represents an integer of 0.1 to 8), etc.