Bihaptinic derivatives for binding for technetium or rhenium, process for their preparation, application for diagnosis and therapy, kits and immunological reactants comprising them

Derivatives comprising two hydrophilic haptens and a potentially effector group of general formula and their salts, in which X represents a hydrogen atom or a protective group which can be used for protecting a thiol functional group against oxidation (CH3CO- or C6H5CO- radical), R1, R2 and R3 each...

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Bibliographic Details
Main Authors GRUAZ-GUYON, ANNE, BARBET, JACQUES, LE DOUSSAL, JEAN-MARC, DELAAGE, MICHEL
Format Patent
LanguageEnglish
French
German
Published 04.05.1994
Edition5
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Summary:Derivatives comprising two hydrophilic haptens and a potentially effector group of general formula and their salts, in which X represents a hydrogen atom or a protective group which can be used for protecting a thiol functional group against oxidation (CH3CO- or C6H5CO- radical), R1, R2 and R3 each represent an amino acid and H1 and H2 represent hydrophilic haptens; process of preparation; application in diagnosis and in therapeutics, diagnostic or therapeutic kits and immunological reagents containing them. Dérivés comprenant deux haptènes hydrophiles et un groupement potentiellement effecteur de formule générale ainsi que leurs sels, dans laquelle X représente un atome d'hydrogène ou un groupe protecteur utilisable pour protéger une fonction thiol contre l'oxydation (radical CH3CO- ou C6H5CO-), R1, R2 et R3 représentent chacun un acide aminé et H1 et H2 représentent des haptènes hydrophiles ; procédé de préparation ; application au diagnostic et à la thérapeutique , kits diagnostiques ou thérapeutiques et réactifs immunologiques les renfermant.
Bibliography:Application Number: EP19930430015