Cephalosporin compounds and processes for the preparation thereof

• Main Authors: NAHM, KEE PYUNG, KIM, YONG ZU, SEO, MI KYEONG, BANG, CHAN SIK, YEO, JAE HONG, LIM, JONG CHAN, OH, HUN SEUNG
• Format: Patent
• Language: English; French; German
• Published: 09.02.1994
• Edition: 5
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a cephalosporin compound including the pharmaceutically acceptable non-toxic salts, physiologically hydrolyzable esters, hydrates and solvates thereof of the formula(I) and its isomers: wherein: R is a C1-4 alkyl, C3-4 alkenyl, C3-4 alkynyl or -C(R)(R)-COOH wherein R and R are, independently of each other, a hydrogen or a C1-4 alkyl group, respectively, or jointly form a C3-7 cycloalkyl group together with the carbon atoms to which they are attached; R is a hydrogen or an amino which may be substituted or unsubstituted, alkoxy or heterocyclic group which is linked with a nitrogen atom; R is a hydrogen or a C1-4 alkyl, amino, aminomethyl, hydroxy, hydroxymethyl, carboxy or carboxymethyl group; R is a hydrogen or a C1-4 alkyl, amino, hydroxy, hydroxyalkl, acetamide, carboxyalkyl or sulfonylethyl group; R is a hydrogen or a C1-4 alkyl, amino, carboxy, carboxyalkyl or hydroxy group; and Q and T are independently CH or N, provided that R is an amino group when T is N.