Liposome formulation and process for production thereof

A liposome formulation comprising liposomes entrapping a drug-containing solution having an osmotic pressure 2.0 to 5.0 times higher than the physiological osmotic pressure, said liposome being small unilamellar vesicle liposomes having an average particle diameter of not more than 0.1 mu m and havi...

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Main Authors INOUE, KIMIO, FUNADA, SATORU, SAWAHARA, HIDEYUKI, ISHIMARU, SUEAKI, TSUNEMI, SHINOBU, SHIBATA, MASAHIKO
Format Patent
LanguageEnglish
French
German
Published 13.10.1993
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract A liposome formulation comprising liposomes entrapping a drug-containing solution having an osmotic pressure 2.0 to 5.0 times higher than the physiological osmotic pressure, said liposome being small unilamellar vesicle liposomes having an average particle diameter of not more than 0.1 mu m and having a phase transfer temperature of the membrane of 40 DEG C to 45 DEG C.
AbstractList A liposome formulation comprising liposomes entrapping a drug-containing solution having an osmotic pressure 2.0 to 5.0 times higher than the physiological osmotic pressure, said liposome being small unilamellar vesicle liposomes having an average particle diameter of not more than 0.1 mu m and having a phase transfer temperature of the membrane of 40 DEG C to 45 DEG C.
Author SHIBATA, MASAHIKO
ISHIMARU, SUEAKI
TSUNEMI, SHINOBU
SAWAHARA, HIDEYUKI
FUNADA, SATORU
INOUE, KIMIO
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– fullname: SHIBATA, MASAHIKO
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DocumentTitleAlternate Liposomenformulierung und deren Herstellungsverfahren.
Formulation liposomique et son procédé de fabrication.
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Snippet A liposome formulation comprising liposomes entrapping a drug-containing solution having an osmotic pressure 2.0 to 5.0 times higher than the physiological...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Liposome formulation and process for production thereof
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