Liposome formulation and process for production thereof

A liposome formulation comprising liposomes entrapping a drug-containing solution having an osmotic pressure 2.0 to 5.0 times higher than the physiological osmotic pressure, said liposome being small unilamellar vesicle liposomes having an average particle diameter of not more than 0.1 mu m and havi...

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Main Authors INOUE, KIMIO, FUNADA, SATORU, SAWAHARA, HIDEYUKI, ISHIMARU, SUEAKI, TSUNEMI, SHINOBU, SHIBATA, MASAHIKO
Format Patent
LanguageEnglish
French
German
Published 13.10.1993
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Summary:A liposome formulation comprising liposomes entrapping a drug-containing solution having an osmotic pressure 2.0 to 5.0 times higher than the physiological osmotic pressure, said liposome being small unilamellar vesicle liposomes having an average particle diameter of not more than 0.1 mu m and having a phase transfer temperature of the membrane of 40 DEG C to 45 DEG C.
Bibliography:Application Number: EP19930302734