2-PHENYL-AND 2-THIENYL-(2)-PIPERIDINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES

Compounds of formula (I) (I) in which R1 is hydrogen, R2 is hydrogen or C1-6 alkyl, R3 and R4 independently represent one or more radicals selected from hydrogen, NH2, NO2, halogen, hydroxy, C1-6 alkoxy or C1-6 alkyl, X represents S or -CH=CH- group and pharmaceutically acceptable salts are NMDA rec...

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Bibliographic Details
Main Authors MURRAY, ROBERT JOHN, GRIFFITH, RONALD CONRAD, SCHMIESING, RICHARD JOHN
Format Patent
LanguageEnglish
French
German
Published 04.06.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of formula (I) (I) in which R1 is hydrogen, R2 is hydrogen or C1-6 alkyl, R3 and R4 independently represent one or more radicals selected from hydrogen, NH2, NO2, halogen, hydroxy, C1-6 alkoxy or C1-6 alkyl, X represents S or -CH=CH- group and pharmaceutically acceptable salts are NMDA receptor antagonists.
Bibliography:Application Number: EP19910920369