QUATERNARY AMMONIUM SALTS DERIVED FROM CHITOSAN

Quaternary ammonium salts of chitosan possessing hypocholesterolemic activity of formula (II) in which A represents the monomer unit of a chitosan, m is a whole number between 100 and 1,000, R1 is C1-C4 linear alkyl and X is a physiologically acceptable water soluble polyanion, where n is at least 1...

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Bibliographic Details
Main Authors CHANDLER, CHARLES, EDWARD, CURATOLO, WILLIAM, JOHN
Format Patent
LanguageEnglish
French
German
Published 02.11.1995
Edition5
Subjects
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Summary:Quaternary ammonium salts of chitosan possessing hypocholesterolemic activity of formula (II) in which A represents the monomer unit of a chitosan, m is a whole number between 100 and 1,000, R1 is C1-C4 linear alkyl and X is a physiologically acceptable water soluble polyanion, where n is at least 10 but not greater than about 10,000, and any remaining positive charges are balanced by nonpolymeric anions.
Bibliography:Application Number: EP19910916756