A METHOD OF PREPARING PYRIDAZINONE DERIVATIVES

A method for the preparation of a pyridazinone derivative having general formula (I), where: R is a phenyl group, optionally substituted, R is H, alkyl or carboxy, R is H, alkyl or alkoxy and R is alkyl; said method comprising reacting a hydrazone of glyoxylic acid halide having formula (VII) in whi...

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Bibliographic Details
Main Authors HOWARTH, MICHAEL, COX, BRIAN, GEOFFREY
Format Patent
LanguageEnglish
French
German
Published 16.10.1996
Edition6
Subjects
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Summary:A method for the preparation of a pyridazinone derivative having general formula (I), where: R is a phenyl group, optionally substituted, R is H, alkyl or carboxy, R is H, alkyl or alkoxy and R is alkyl; said method comprising reacting a hydrazone of glyoxylic acid halide having formula (VII) in which X is halogen, with an ester of formula (VIII) in the presence of an alkaline earth base.
Bibliography:Application Number: EP19900913854