AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTITUTED ISOFLAVONE DERIVATIVES

PCT No. PCT/HU90/00023 Sec. 371 Date Dec. 5, 1991 Sec. 102(e) Date Dec. 5, 1991 PCT Filed Apr. 6, 1990 PCT Pub. No. WO91/15483 PCT Pub. Date Oct. 17, 1991.The invention relates to a process for the preparation of pure isoflavone derivatives of the general formula (I), (I) wherein R stands for hydrog...

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Main Authors SZILADI, MARIA, SOMFAI, EVA, HOFFMANN, GYOERGY, MONTAY, TIBOR, KALLAY, TAMAS, LANYI, GYOERGY, IMREI, LAJOS, LEDNICZKY, LASZLO
Format Patent
LanguageEnglish
French
German
Published 02.02.1994
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PCT No. PCT/HU90/00023 Sec. 371 Date Dec. 5, 1991 Sec. 102(e) Date Dec. 5, 1991 PCT Filed Apr. 6, 1990 PCT Pub. No. WO91/15483 PCT Pub. Date Oct. 17, 1991.The invention relates to a process for the preparation of pure isoflavone derivatives of the general formula (I), (I) wherein R stands for hydrogen or isopropyl, R2 and R3 stand for hydrogen or C1-2 alkoxy by reacting a rezorcinol-derivative of the general formula (III) (III) wherein R2 and R3 are as given above with ethyl-orthoformiate of the formula (IV) (C2H5O)3l CH(IV) in the presence of a base and optionally by alkylating the product.
Bibliography:Application Number: EP19900906260