Fused 7-membered cyclic compound and antipsychotic preparation containing the same

A fused cyclic compound having the formula (I) or salts thereof: wherein both of A and B are carbonyl groups, or one represents methylene group and the other carbonyl group, Z represents a sulfur atom, or a nitrogen atom which may be substituted, or a methylene group, R represents an aromatic or het...

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Bibliographic Details
Main Authors TATSUOKA, TOSHIO, NOMURA, KAYOKO
Format Patent
LanguageEnglish
French
German
Published 04.09.1991
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A fused cyclic compound having the formula (I) or salts thereof: wherein both of A and B are carbonyl groups, or one represents methylene group and the other carbonyl group, Z represents a sulfur atom, or a nitrogen atom which may be substituted, or a methylene group, R represents an aromatic or heterocyclic group, which may be substituted, X represents a hydrogen atom, a halogen atom, a C1 - C5 lower alkyl group, a C1 - C5 lower alkoxy group, a C7 - C9 arylalkoxy group, a C1 - C5 lower acyloxy group, a C7 - C10 arylcarbonyloxy group, a hydroxy group, a nitro group or an ester group, and n is an integer of 2 to 10. The compounds have affinity for serotonin receptor.
Bibliography:Application Number: EP19910301633