NON-BIODEGRADABLE, TWO-PHASE CORNEAL IMPLANT AND METHOD FOR PREPARING SAME

The present invention provides a non-biodegradable corneal implant comprising (1) a polymerized transparent collagenous core having acylated amine or esterified carboxyl groups, and (2) a polymerized periphery surrounding the core, the periphery comprising fibrous collagen, e.g., Type I, being in th...

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Bibliographic Details
Main Authors KELMAN, CHARLES D, DEVORE, DALE P
Format Patent
LanguageEnglish
Published 24.02.1993
Edition5
Subjects
BANDAGES, DRESSINGS OR ABSORBENT PADS
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROSTHESES
THEIR PREPARATION OR CHEMICAL WORKING-UP
TREATMENT OR PROTECTION OF EYES OR EARS
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Summary:The present invention provides a non-biodegradable corneal implant comprising (1) a polymerized transparent collagenous core having acylated amine or esterified carboxyl groups, and (2) a polymerized periphery surrounding the core, the periphery comprising fibrous collagen, e.g., Type I, being in the form of fibrils under suitable physiological conditions, or fibrillar collagenous material prepared from intact tissue. A method of preparing such an implant is also provided.
Bibliography:Application Number: EP19900120636