METHOD OF PRODUCING A TASTE-MASKED ORAL PREPARATION

A flavoring oral preparation is produced in a high yield by spraying in a wet hot air a suspension of a drug or particles containing it in a cooled aqueous solution of polyvinyl acetal diethylaminoacetate and drying the formed minute particles. The obtained preparation is excellent in the effect of...

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Bibliographic Details
Main Authors MAKABE, ERI, KOYAMA, IKUO, SHIMANO, KIMIHIDE 2-29-402, OZAWA, YASUO
Format Patent
LanguageEnglish
French
German
Published 10.04.1991
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A flavoring oral preparation is produced in a high yield by spraying in a wet hot air a suspension of a drug or particles containing it in a cooled aqueous solution of polyvinyl acetal diethylaminoacetate and drying the formed minute particles. The obtained preparation is excellent in the effect of masking a drug having a disagreeable taste and has a good bioavailability equivalent to that of the drug itself. On produit une préparation orale aromatique avec un rendement élevé en pulvérisant dans de l'air chaud humide une suspension d'un médicament ou des particules le contenant dans une solution aqueuse refroidie de diéthylaminoacétate de polyvinylacétal et en séchant les minuscules particules formées. La préparation obtenue est excellente pour masquer le goût désagréable d'un médicament et présente une bonne biodisponibilité équivalente à celle du médicament lui-même.
Bibliography:Application Number: EP19900905690