Naphthopyran compounds

A compound of formula (I) wherein R1 represents hydrogen, hydroxy or acetoxy and R2 represents hydroxy or acetoxy. The compounds are capable of protecting the nerve cells and also antagonistic activity against N-methyl-D-aspartic acid receptors. They may be prepared by fermentation of a microorganis...

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Bibliographic Details
Main Authors YOSHIDA, MAYUMI, ANDO, KATSUHIKO, NOZAWA, MIKA, SANO, HIROSHI, KUBO, KAZUHIRO, IKEDA, JUNICHI, TOKI, SHINICHIRO, MATSUDA, YUZURU, KAWAMOTO, ISAO
Format Patent
LanguageEnglish
French
German
Published 03.04.1991
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:A compound of formula (I) wherein R1 represents hydrogen, hydroxy or acetoxy and R2 represents hydroxy or acetoxy. The compounds are capable of protecting the nerve cells and also antagonistic activity against N-methyl-D-aspartic acid receptors. They may be prepared by fermentation of a microorganism of the genus Verticillium or a mutant thereof.
Bibliography:Application Number: EP19900310172