Disubstituted (quinolin-2-yl-methoxy)-phenylacetic acid derivatives

Disubstituted (quinolin-2-ylmethoxy)phenylacetic acid derivatives can be prepared by reduction of correspondingly disubstituted ketoesters by means of Grignard reagents and, for the preparation of the thio compounds, by subsequent reaction with thiols. The compounds can be used as active substances...

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Main Authors FRUCHTMANN, ROMANIS, KOHLSDORFER, CHRISTIAN, THEISEN-POPP, PIA, RADDATZ, SIEGFRIED, MUELLER-PEDDINGHAUS, REINER, MOHRS, KLAUS
Format Patent
LanguageEnglish
French
German
Published 01.06.1994
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disubstituted (quinolin-2-ylmethoxy)phenylacetic acid derivatives can be prepared by reduction of correspondingly disubstituted ketoesters by means of Grignard reagents and, for the preparation of the thio compounds, by subsequent reaction with thiols. The compounds can be used as active substances in medicaments.
Bibliography:Application Number: EP19900115444