AROMATIC KETO COMPOUNDS, THEIR PREPARATION AND MEDICINAL AS WELL AS COSMETIC PREPARATIONS CONTAINING THEM

• Main Authors: WUEST, HANS-HEINER, JANSSEN, BERND
• Format: Patent
• Language: English; German
• Published: 22.09.1993
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Compounds of the general formula I in which A denotes an ethylene or methylene radical optionally substituted by a methyl, hydroxyl or oxo group, L denotes one of the groups R and R denotes hydrogen or a methyl radical, R denotes hydrogen, a hydroxyl or a C1-6-alkoxy group, R denotes hydrogen, a C1-4-alkyl radical, a halogen atom or a methoxy group, R denotes hydrogen or a methoxy group and R denotes hydrogen, a methyl or nitrile group, a C2-10-ketal group or the radicals -CHR -OR , -CHR -NR -R , -COR , in which R represents hydrogen or a C1-4-alkyl group, R represents hydrogen, a C1-4-alkyl, C1-20-alkanoyl or an optionally substituted benzoyl group, R and R represent hydrogen atoms, C1-4-alkyl, C1-6-alkanoyl or optionally substituted benzoyl groups or, together with the nitrogen atom to which they are bonded, represent a 5- or 6-membered, saturated heterocyclic radical, which apart from the nitrogen atom can additionally contain an oxygen atom, R represents hydrogen, a C1-4-alkyl group or the radicals -OR or -NR R with R denoting a hydrogen atom, a C1-8-alkyl group optionally substituted by 1 or 2 hydroxyl groups, an optionally substituted aryl group or an aralkyl group optionally substituted in the aryl moiety, and with R and R denoting hydrogen atoms, optionally substituted aralkyl or aryl groups, or R and R , together with the nitrogen to which they are bonded, denoting a 5- or 6-membered saturated heterocyclic radical, which apart from the nitrogen atom can additionally contain an oxygen atom, and R denotes a C1-4-alkyl group, and their physiologically tolerable salts, process for their preparation and medicaments and cosmetics prepared from them.