Improved process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic acid

An improved process for the preparation of 3-chloro-2,4,5-trifluorobenzoic acid is described which involves reaction of a diester of 3,4,5,6-tetrafluoro-1,2-benzenedicarboxylic acid with a substituted amine to afford 3-amino-2,4,5-trifluorobenzoic acid followed by subsequent conversion of the amino...

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Bibliographic Details
Main Authors KARRICK, GREGORY LEE, SPENCE, FLOYD GREGORY, WEMPLE, JAMES NORTON
Format Patent
LanguageEnglish
French
German
Published 02.05.1990
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:An improved process for the preparation of 3-chloro-2,4,5-trifluorobenzoic acid is described which involves reaction of a diester of 3,4,5,6-tetrafluoro-1,2-benzenedicarboxylic acid with a substituted amine to afford 3-amino-2,4,5-trifluorobenzoic acid followed by subsequent conversion of the amino intermediate into 3-chloro-2,4,5-trifluorobenzoic acid.
Bibliography:Application Number: EP19890120030