PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS

A process for producing an L-amino acid of formula (I): wherein R is -CH2CO2H, -CH2CONH2, -CO2H or in which R is a hydrogen atom, an alkyl group having 1 to 10 carbon atoms or a halogen-substituted alkyl group having 1 to 10 carbon atoms, which process comprises carrying out an optical resolution of...

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Bibliographic Details
Main Authors SHINKE, SHUZO, TAGAWA, MICHITO, NARUSHIMA, HIROYUKI, FURUSATO, TAKASHI, KUWAHARA, MASAO
Format Patent
LanguageEnglish
Published 03.07.1991
Edition5
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Summary:A process for producing an L-amino acid of formula (I): wherein R is -CH2CO2H, -CH2CONH2, -CO2H or in which R is a hydrogen atom, an alkyl group having 1 to 10 carbon atoms or a halogen-substituted alkyl group having 1 to 10 carbon atoms, which process comprises carrying out an optical resolution of an N-substituted carbonyl-D,L-amino acid of formula (II): wherein R is as defined above and R is an alkanoyl group having 1 to 5 carbon atoms, a benzoyl group, a halogen-substituted alkanoyl group having 1 to 5 carbon atoms or a halogen-substituted benzoyl group, or a salt thereof, or a mixture thereof, with cells of a microorganism, a microorganism fermentation broth, a treated microorganism fermentation broth, or a mixture thereof, said microorganism being selected from the bacteria of the genera Serratia, Staphylococcus, Bacillus, Flavobacterium Achromobacter and Alcaligenes and actinomycetes of the genera Actinoplanes, Streptosporangium and Sebekia.
Bibliography:Application Number: EP19890308930