PYRIDYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVES AND THEIR INTERMEDIATES AND PRODUCTION OF BOTH

This invention provides pyridylthiazolidine carboxamide derivatives shown by general formula (I) and pharmaceutically acceptable salts thereof: wherein A is a single bond, carbonyl group or lower alkylene group which may include a carbonyl group and R is a heterocyclic ring which may be substituted...

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Bibliographic Details
Main Authors HARA, HIROMU, YAMADA, TOSHIMITSU, MASE, TOSHIYASU
Format Patent
LanguageEnglish
Published 04.07.1990
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention provides pyridylthiazolidine carboxamide derivatives shown by general formula (I) and pharmaceutically acceptable salts thereof: wherein A is a single bond, carbonyl group or lower alkylene group which may include a carbonyl group and R is a heterocyclic ring which may be substituted with a lower alkyl group; it further provides N-substituted piperazine derivatives useful as intermediates for preparing said compounds (I). Compounds (I) and their salts have PAF-antagonistic activity.
Bibliography:Application Number: EP19890303137