Pyrazolopyridine type mevalonolactones

The present invention relates to compounds of the formula: where Y is -CH2-, -CH2CH2-, -CH=CH-, -CH2-CH=CH-, -CH=CH-CH2-, -C(CH3)=CH- or -CH=C(CH3); Z is -Q-CH2WCH2-CO2R , (wherein Q is -C(O)-, -C(OR )2- or -CH(OH)-; W is -C(O)-, -C(OR )2- or -C(R )(OH)-; and their pharmaceutical uses as anti-hyperl...

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Bibliographic Details
Main Authors KITAHARA, MASAKI NISSAN . SEIBUTSUKAGAKU, SUZUKI, MIKIO NISSAN ICAL IND. LTD, IWASAKI, HIROSHI NISSAN ICAL IND. LTD, SAKASHITA, MITSUAKI NISSAN ICAL IND. LTD, FUJIKAWA, YOSHIHIRO NISSAN ICAL IND. LTD
Format Patent
LanguageEnglish
French
German
Published 02.11.1989
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of the formula: where Y is -CH2-, -CH2CH2-, -CH=CH-, -CH2-CH=CH-, -CH=CH-CH2-, -C(CH3)=CH- or -CH=C(CH3); Z is -Q-CH2WCH2-CO2R , (wherein Q is -C(O)-, -C(OR )2- or -CH(OH)-; W is -C(O)-, -C(OR )2- or -C(R )(OH)-; and their pharmaceutical uses as anti-hyperlipidemic, hypolipoproteinemic and anti-atherosclerotic agents.
Bibliography:Application Number: EP19890106401