MOUSE MONOCLONAL ANTIBODY TO HUMAN IMMUNODEFICIENCY VIRUS GP41 PROTEIN

The present invention discloses a monoclonal antibody capable of demonstrating specific reactivity with a conformational epitope on the Human Immunodeficiency Virus I protein gp41. The present invention also provides for a cell line capable of producing such a monoclonal antibody as well as immunolo...

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Bibliographic Details
Main Authors FALK, LAWRENCE A, HUNT, JEFFREY C, SARIN, VIRENDER K, WRAY, LARRY K, DEVARE, SUSHIL G, WEBBER, J. SCOTT, DAWSON, GEORGE J
Format Patent
LanguageEnglish
Published 26.06.1991
Edition4
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The present invention discloses a monoclonal antibody capable of demonstrating specific reactivity with a conformational epitope on the Human Immunodeficiency Virus I protein gp41. The present invention also provides for a cell line capable of producing such a monoclonal antibody as well as immunological procedures for the detection in biological samples of exposure to HIV. The Invention further provides for the use of the monoclonal antibody as a probe against native antigens and synthetic peptides of HIV.
Bibliography:Application Number: EP19890103859