Substituted quinolines and cinnolines

• Main Authors: JOURDAN, GLEN PHIL, DREIKORN, BARRY ALLEN, SUHR, ROBERT GEORGE
• Format: Patent
• Language: English; French; German
• Published: 17.04.2002
• Edition: 7
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; METALLURGY; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

Compounds of the formula (1): wherein: R to R are independently H, halo, (C1-C4) alkyl, branched (C3-C4) alkyl, halo (C1-C4) alkyl, (C1-C4) alkoxy, NO2, or NH2, at least two of R to R being H, or one of R to R is -NR -Y-Ar or O-Y-Ar and the rest of R to R are H; W is N, or CR ; R is H, CH3, Cl, O-Y-Ar, or -NR -Y-Ar; R is H, CH3, Cl or Br; A is -O-Alk or -X-Y-Ar; Alk is a C2-C18 saturated or unsaturated hydrocarbon chain, straight chain or branched, optionally substituted with halo, halo (C1-C4) alkoxy, (C3-C8) cycloalkyl, hydroxy, or acetyl; X is O, NR , or CR R , provided that if one of R to R is NR -Y-Ar or O-Y-Ar, then X-Y-Ar is an identical group; R is H, (C1-C4) alkyl, or acetyl; R and R are independently H, (C1-C4) alkyl, (C1-C4) acyl, halo, or OH, or R and R combine to form a saturated or unsaturated carbocyclic ring comprising three to seven carbon atoms; Y is an alkylene chain 2 to 8 carbon atoms long, optionally including an O, S, SO, SO2, or NR group or a saturated or unsaturated carbocyclic ring comprising three to seven carbon atoms, or substituted with (C1-C3) alkyl, (C2-C4) alkenyl, phenyl, (C3-C8) cycloalkyl, hydroxy, halo, or (C1-C4) acyl; and Ar is 1,3-benzodioxolyl fluorenyl, pyridyl, imidazolyl, indolyl, thienyl, optionally substituted with CH3 or Cl, thiazolyl, cyclopentyl, 1-methylcyclopentyl, cyclohexenyl (hexahydrophenyl), cyclohexyl (tetrahydrophenyl), naphthyl, dihydronaphthyl, tetrahydronaphthyl, decahydronaphthyl, or a group of the formula (2): where R to R are independently H, halo, I, (C1-C10) alkyl, branched (C3-C6) alkyl, halo (C1-C4) alkyl, (C1-C4) alkoxy, halo (C1-C4) alkoxy, phenoxy, substituted phenoxy, phenylthio, substituted phenylthio, phenyl, substituted phenyl, NO2, NH2, acetoxy, OH, CN, or SiR R R , OSir , R , R , where R , R , and R are independently (C1-C4) alkyl or (C3-C4) branched alkyl, provided that unless each of R to R is F, CH3, or H, then at least two of R to R are H; or an acid addition salt of a compound of formula (1) or an N-oxide of a compound of formula (1) when W is CR are fungicides, insecticides, and miticides.