PROCESS FOR THE PREPARATION OF CYSTEAMINE ACID ADDITION SALTS

The cysteamine acid addition salts are prepared by reaction of aziridine with an organic sulphur compound of oxidation state -2 and with a ketone, followed by acid hydrolysis of the thiazolidine formed as intermediate, the aziridine and the ketone being reacted with ammonium hydrogen sulphide or a m...

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Bibliographic Details
Main Authors HOHMANN, ANDREAS, REUTHER, WOLFGANG, PROLL, THEO, FIKENTSCHER, ROLF
Format Patent
LanguageEnglish
German
Published 02.01.1992
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The cysteamine acid addition salts are prepared by reaction of aziridine with an organic sulphur compound of oxidation state -2 and with a ketone, followed by acid hydrolysis of the thiazolidine formed as intermediate, the aziridine and the ketone being reacted with ammonium hydrogen sulphide or a metal hydrogen sulphide with the addition of a medium to strong acid at a temperature of -10 to +100 DEG C and a pH of greater than or equal to 8.5 being maintained.
Bibliography:Application Number: EP19880120207