METHODS AND APPARATUS FOR THE QUANTITATION OF NUCLEAR PROTEINS

A method of measuring the quantity of a specific nuclear protein in a cell/population, particularly in order to predict the prognosis of endocrine manipulative management in treating a carcinoma, comprises staining a sample of the cell population with at least one image enhancement factor which has...

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Bibliographic Details
Main Author BACUS, JAMES WILLIAM
Format Patent
LanguageEnglish
Published 04.09.1991
Edition4
Subjects
CALCULATING
COMPUTING
COUNTING
HANDLING RECORD CARRIERS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
PRESENTATION OF DATA
RECOGNITION OF DATA
RECORD CARRIERS
TESTING
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Summary:A method of measuring the quantity of a specific nuclear protein in a cell/population, particularly in order to predict the prognosis of endocrine manipulative management in treating a carcinoma, comprises staining a sample of the cell population with at least one image enhancement factor which has an optical density which varies with the quantity of nuclear protein contained within said sample; measuring the optical density of said sample; and calibrating the measured optical density of said sample to the quantity of nuclear protein contained within said sample. An apparatus for carrying out the method is also disclosed.
Bibliography:Application Number: EP19880309264