Fibrinolytically active enzyme

A fibrinolytically active hybrid enzyme which comprises the A chain of plasmin linked to the B chain of a plasminogen activator selected from tissue-type plasminogen activator and urokinase plasminogen activator, characterised in that said chains are linked by peptide bonds via an amino acid sequenc...

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Bibliographic Details
Main Author BROWNE, MICHAEL JOSEPH BEECHAM PHARMACEUTICALS
Format Patent
LanguageEnglish
French
German
Published 09.11.1988
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:A fibrinolytically active hybrid enzyme which comprises the A chain of plasmin linked to the B chain of a plasminogen activator selected from tissue-type plasminogen activator and urokinase plasminogen activator, characterised in that said chains are linked by peptide bonds via an amino acid sequence comprising the cleavage site of plasminogen.
Bibliography:Application Number: EP19880301897