A SOLUTION FOR STABILIZING RED BLOOD CELLS DURING STORAGE

• Main Authors: GRODE, GERALD, A, KANDLER, RICHARD, L
• Format: Patent
• Language: English; French; German
• Published: 16.12.1987
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Une solution de stabilisation des cellules rouges du sang pendant leur stockage contient, outre les substances nutritives et autres éléments stabilisateurs, une concentration sûre et effective d'un inhibiteur d'une étape du chemin métabolique de la glycolyse qui est consécutive à l'étape qui forme 2,3-DPG. L'inhibiteur peut être l'acide oxalique, l'oxalate de sodium, l'oxalate de potassium ou des sels mélangés de ceux-ci, par exemple. A solution for stabilizing red blood cells during storage contains, along with nutrients and other stabilizers, a safe and effective concentration of an inhibitor of a step of the glycolysis metabolic pathway which is subsequent to the step which forms 2,3-DPG. The inhibitor may be oxalic acid, sodium oxalate, potassium oxalate, or mixed salts thereof, for example.