ALKENAMIDE DERIVATIVES

The invention concerns novel N-[4(Z)-2-substituted-6-(4-o-hydroxyphenyl-1,3 dioxan-cis-5-yl) hexenoyl]sulphonamide derivatives of formula I of value as therapeutic agents. Typically R is a branched (3-6C)alkyl, trifluoromethyl or phenyl radical as defined hereinafter and R is alkyl, benzyl or phenyl...

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Bibliographic Details
Main Authors BROWN, GEORGE ROBERT, SMITHERS, MICHAEL JAMES
Format Patent
LanguageEnglish
Published 27.11.1991
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention concerns novel N-[4(Z)-2-substituted-6-(4-o-hydroxyphenyl-1,3 dioxan-cis-5-yl) hexenoyl]sulphonamide derivatives of formula I of value as therapeutic agents. Typically R is a branched (3-6C)alkyl, trifluoromethyl or phenyl radical as defined hereinafter and R is alkyl, benzyl or phenyl. The invention also discloses salts of the formula I compounds as well as pharmaceutical compositions containing the compounds and processes for the production of the compounds.
Bibliography:Application Number: EP19870303832