1,2,4-TRIAZINONE DERIVATIVES, THEIR PREPARATION AND USE
Compounds of formula (I): (I) (in which: R1 is hydrogen or alkl; R2 is a variety of groups or atoms; R3 is optionally substituted hydroxy or -(NH)n-NR5R6, wherein R5 and R6 are a variety of groups or atoms, preferably alkyl substituted by heterocyclic, and n is 0 or 1; Q is oxygen or sulfur; and A i...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | English |
Published |
05.10.1988
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Edition | 4 |
Subjects | |
Online Access | Get full text |
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Summary: | Compounds of formula (I): (I) (in which: R1 is hydrogen or alkl; R2 is a variety of groups or atoms; R3 is optionally substituted hydroxy or -(NH)n-NR5R6, wherein R5 and R6 are a variety of groups or atoms, preferably alkyl substituted by heterocyclic, and n is 0 or 1; Q is oxygen or sulfur; and A is a C1-C6 alkylene group) have valuable cardiotionic activity and may be used for the treatment of cardiac disorders. They may be prepared from corresponding compounds containing a benzene ring with a group -QH at the 1-position and a group -CO-CHR1-NH-COOR7 at the 4-position by ring closure and introduction of the group of formula -A-CO-R3 in any order. |
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Bibliography: | Application Number: EP19870302443 |